Comprehensive Meta-Analysis (CMA) Version 4 is a user-friendly yet powerful software for conducting meta-analyses, featuring an intuitive spreadsheet interface, advanced statistical tools (like subgroup analysis, meta-regression, publication bias tests), high-resolution graph generation (e.g., forest plots with prediction intervals), and options for easy data import/export, making complex research accessible for novices and experts alike, with key updates in V4 including video tutorials, prediction intervals, and better reporting.